Accumulation of a novel spliceosomal complex on pre-mRNAs containing branch site mutations.

Pre-mRNA assembles into spliceosomal complexes in the stepwise pathway E-->A-->B-->C. We show that mutations in the metazoan branchpoint sequence (BPS) have no apparent effect on E complex formation but block the assembly of the A complex and the UV cross-linking of U2 small nuclear ribonuc...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Champion-Arnaud, P, Gozani, O, Palandjian, L, Reed, R
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1995
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC230826/
https://ncbi.nlm.nih.gov/pubmed/7565727
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