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A central role for a single c-Myb binding site in a thymic locus control region.

Locus control regions (LCRs) are powerful assemblies of cis elements that organize the actions of cell-type-specific trans-acting factors. A 2.3-kb LCR in the human adenosine deaminase (ADA) gene first intron, which controls expression in thymocytes, is composed of a 200-bp enhancer domain and exten...

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Hlavní autoři: Ess, K C, Whitaker, T L, Cost, G J, Witte, D P, Hutton, J J, Aronow, B J
Médium: Artigo
Jazyk:Inglês
Vydáno: 1995
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC230821/
https://ncbi.nlm.nih.gov/pubmed/7565722
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