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The nonreceptor protein-tyrosine kinase CSK complexes directly with the GTPase-activating protein-associated p62 protein in cells expressing v-Src or activated c-Src.

CSK is a predominantly cytosolic protein-tyrosine kinase (PTK) that negatively regulates Src family PTKs by phosphorylation of a conserved tyrosine near their C termini. Little is known about how CSK itself is regulated. On the basis of immunofluorescence studies, a model has been proposed that when...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Neet, K, Hunter, T
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230737/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7544435/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.9.4908
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