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Functional effects of a natural polymorphism in the transcriptional regulatory sequence of HLA-DQB1.

DNA sequence polymorphism in the genes encoding HLA class II proteins accounts for allelic diversity in antigen recognition and presentation and, thus, in the role of these cell surface glycoproteins as determinants of the scope of the T-cell repertoire. In addition, sequence polymorphism in the pro...

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Detalhes bibliográficos
Main Authors: Beaty, J S, West, K A, Nepom, G T
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC230721/
https://ncbi.nlm.nih.gov/pubmed/7651394
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