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A domain of the even-skipped protein represses transcription by preventing TFIID binding to a promoter: repression by cooperative blocking.

We examined the mechanism by which the C-terminal 236 amino acids of the even-skipped protein (region CD) repress transcription. A fusion protein, CDGB, was created that contains region CD fused to the glucocorticoid receptor DNA binding domain. This protein repressed transcription in an in vitro sy...

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Pubblicato in:Mol Cell Biol
Autori principali: Austin, R J, Biggin, M D
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 1995
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230711/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7651385/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.9.4683
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