The histidyl-tRNA synthetase-related sequence in the eIF-2 alpha protein kinase GCN2 interacts with tRNA and is required for activation in response to starvation for different amino acids.

Ítems similars

• Mutations activating the yeast eIF-2 alpha kinase GCN2: isolation of alleles altering the domain related to histidyl-tRNA synthetases.
  per: Ramirez, M, et al.
  Publicat: (1992)
• Juxtaposition of domains homologous to protein kinases and histidyl-tRNA synthetases in GCN2 protein suggests a mechanism for coupling GCN4 expression to amino acid availability.
  per: Wek, R C, et al.
  Publicat: (1989)
• GCN2-like eIF2α kinase manages the amino acid starvation response in Toxoplasma gondii
  per: Konrad, Christian, et al.
  Publicat: (2013)
• Multicopy tRNA genes functionally suppress mutations in yeast eIF-2 alpha kinase GCN2: evidence for separate pathways coupling GCN4 expression to unchanged tRNA.
  per: Vazquez de Aldana, C R, et al.
  Publicat: (1994)
• Genome-wide Analysis of tRNA Charging and Activation of the eIF2 Kinase Gcn2p
  per: Zaborske, John M., et al.
  Publicat: (2009)