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Studies of point mutants define three essential paired nucleotides in the domain 5 substructure of a group II intron.

Domain 5 (D5) is a highly conserved, largely helical substructure of group II introns that is essential for self-splicing. Only three of the 14 base pairs present in most D5 structures (A2.U33, G3.U32, and C4.G31) are nearly invariant. We have studied effects of point mutations of those six nucleoti...

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Détails bibliographiques
Auteurs principaux: Boulanger, S C, Belcher, S M, Schmidt, U, Dib-Hajj, S D, Schmidt, T, Perlman, P S
Format: Artigo
Langue:Inglês
Publié: 1995
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC230687/
https://ncbi.nlm.nih.gov/pubmed/7623838
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