RelA is a potent transcriptional activator of the CD28 response element within the interleukin 2 promoter.

T-cell activation requires two different signals. The T-cell receptor's recognition of a specific antigen on antigen-presenting cells provides one, and the second signal comes from costimulatory molecules such as CD28. In contrast, T cells that are stimulated with antigen in the absence of the CD28...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Lai, J H, Horvath, G, Subleski, J, Bruder, J, Ghosh, P, Tan, T H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230665/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7623820/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.8.4260
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