Rapid mRNA degradation mediated by the c-fos 3' AU-rich element and that mediated by the granulocyte-macrophage colony-stimulating factor 3' AU-rich element occur through similar polysome-associated mechanisms.

The different 3' noncoding AU-rich elements (ARE) that mediate the degradation of many short-lived mRNAs may function through distinct decay pathways; translation-dependent and -independent mechanisms have been proposed. To investigate the cotranslational model, we designed an expression system...

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Main Authors: Winstall, E, Gamache, M, Raymond, V
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC230618/
https://ncbi.nlm.nih.gov/pubmed/7540719
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