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Proviral insertions induce the expression of bone-specific isoforms of PEBP2αA (CBFA1): Evidence for a new myc collaborating oncogene

The til-1 locus was identified as a common retroviral integration site in virus-accelerated lymphomas of CD2-myc transgenic mice. We now show that viral insertions at til-1 lead to transcriptional activation of PEBP2αA (CBFA1), a transcription factor related to the Drosophila segmentation gene produ...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Stewart, M., Terry, A., Hu, M., O’Hara, M., Blyth, K., Baxter, E., Cameron, E., Onions, D. E., Neil, J. C.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1997
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23059/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9238031/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.16.8646
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