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Myristoylation and differential palmitoylation of the HCK protein-tyrosine kinases govern their attachment to membranes and association with caveolae.

The human proto-oncogene HCK encodes two versions of a protein-tyrosine kinase, with molecular weights of 59,000 (p59hck) and 61,000 (p61hck). The two proteins arise from a single mRNA by alternative initiations of translation. In this study, we explored the functions of these proteins by determinin...

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Autores principales: Robbins, S M, Quintrell, N A, Bishop, J M
Formato: Artigo
Lenguaje:Inglês
Publicado: 1995
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC230587/
https://ncbi.nlm.nih.gov/pubmed/7791757
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