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Molecular cloning and expression of human cDNAs encoding a novel DNA ligase IV and DNA ligase III, an enzyme active in DNA repair and recombination.

Three distinct DNA ligases, I to III, have been found previously in mammalian cells, but a cloned cDNA has been identified only for DNA ligase I, an essential enzyme active in DNA replication. A short peptide sequence conserved close to the C terminus of all known eukaryotic DNA ligases was used to...

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Publicat a:Mol Cell Biol
Autors principals: Wei, Y F, Robins, P, Carter, K, Caldecott, K, Pappin, D J, Yu, G L, Wang, R P, Shell, B K, Nash, R A, Schär, P
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230553/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7760816/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.6.3206
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