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DNA-binding and chromatin localization properties of CHD1.

CHD1 is a novel DNA-binding protein that contains both a chromatin organization modifier (chromo) domain and a helicase/ATPase domain. We show here that CHD1 preferentially binds to relatively long A.T tracts in double-stranded DNA via minor-groove interactions. Several CHD1-binding sites were found...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Stokes, D G, Perry, R P
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1995
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230505/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7739555/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.5.2745
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