Cyclin D1 is dispensable for G1 control in retinoblastoma gene-deficient cells independently of cdk4 activity.

To elucidate the regulator-versus-target relationship in the cyclin D1/cdk4/retinoblastoma protein (pRB) pathway, we examined fibroblasts from RB-1 gene-deficient and RB-1 wild-type littermate mouse embryos (ME) and in human tumor cell lines that differed in the status of the RB-1 gene. The RB+/+ an...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Lukas, J, Bartkova, J, Rohde, M, Strauss, M, Bartek, J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230490/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7739541/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.5.2600
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