Induction of homologous recombination in mammalian chromosomes by using the I-SceI system of Saccharomyces cerevisiae.

The mitochondrial intron-encoded endonuclease I-SceI of Saccharomyces cerevisiae has an 18-bp recognition sequence and, therefore, has a very low probability of cutting DNA, even within large genomes. We demonstrate that double-strand breaks can be initiated by the I-SceI endonuclease at a predeterm...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Choulika, A, Perrin, A, Dujon, B, Nicolas, J F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230423/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7891691/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.4.1968
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