The transcriptional activator GCN4 contains multiple activation domains that are critically dependent on hydrophobic amino acids.

Ítems similars

• Identification of seven hydrophobic clusters in GCN4 making redundant contributions to transcriptional activation.
  per: Jackson, B M, et al.
  Publicat: (1996)
• Separate domains in GCN1 for binding protein kinase GCN2 and ribosomes are required for GCN2 activation in amino acid-starved cells
  per: Sattlegger, Evelyn, et al.
  Publicat: (2000)
• Identification of positive-acting domains in GCN2 protein kinase required for translational activation of GCN4 expression.
  per: Wek, R C, et al.
  Publicat: (1990)
• Multiple GCD genes required for repression of GCN4, a transcriptional activator of amino acid biosynthetic genes in Saccharomyces cerevisiae.
  per: Harashima, S, et al.
  Publicat: (1986)
• Juxtaposition of domains homologous to protein kinases and histidyl-tRNA synthetases in GCN2 protein suggests a mechanism for coupling GCN4 expression to amino acid availability.
  per: Wek, R C, et al.
  Publicat: (1989)