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The transcriptional activator GCN4 contains multiple activation domains that are critically dependent on hydrophobic amino acids.

GCN4 is a transcriptional activator in the bZIP family that regulates amino acid biosynthetic genes in the yeast Saccharomyces cerevisiae. Previous work suggested that the principal activation domain of GCN4 is a highly acidic segment of approximately 40 amino acids located in the center of the prot...

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Detalhes bibliográficos
Main Authors: Drysdale, C M, Dueñas, E, Jackson, B M, Reusser, U, Braus, G H, Hinnebusch, A G
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC230345/
https://ncbi.nlm.nih.gov/pubmed/7862116
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