Thyrotropin-induced mitogenesis is Ras dependent but appears to bypass the Raf-dependent cytoplasmic kinase cascade.

Ítems similars

• Inhibition of thyrotropin-stimulated DNA synthesis by microinjection of inhibitors of cellular Ras and cyclic AMP-dependent protein kinase.
  per: Kupperman, E, et al.
  Publicat: (1993)
• Regulation of Raf-1 and Raf-1 mutants by Ras-dependent and Ras-independent mechanisms in vitro.
  per: Dent, P, et al.
  Publicat: (1995)
• An intact Raf zinc finger is required for optimal binding to processed Ras and for ras-dependent Raf activation in situ.
  per: Luo, Z, et al.
  Publicat: (1997)
• Differential regulation of Raf-1 and B-Raf and Ras-dependent activation of mitogen-activated protein kinase by cyclic AMP in PC12 cells.
  per: Erhardt, P, et al.
  Publicat: (1995)
• GTP-dependent association of Raf-1 with Ha-Ras: identification of Raf as a target downstream of Ras in mammalian cells.
  per: Koide, H, et al.
  Publicat: (1993)