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Vaccination against persistent viral infection exacerbates CD4+ T-cell-mediated immunopathological disease.

Lymphocytic choriomeningitis virus (LCMV) infection of normal mice results in a fatal immunopathologic meningitis mediated by CD8+ cytotoxic T lymphocytes (CTL). We have previously shown that female beta2-microglobulin-deficient (beta2m-/-) mice, which are also deficient in CD8+ T cells, are suscept...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Hildeman, D, Yañez, D, Pederson, K, Havighurst, T, Muller, D
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1997
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230276/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9371632/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.12.9672-9678.1997
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