E1A 12S and 13S of the transformation-defective adenovirus type 12 strain CS-1 inactivate proteins of the RB family, permitting transactivation of the E2F-dependent promoter.

The transformation-defective Vero cell host range mutant CS-1 of the highly oncogenic adenovirus type 12 (Ad12) (Ad12-CS-1) has a 69-bp deletion in the early region 1A (E1A) gene that removes the carboxy-terminal half of conserved region 2 and the amino-terminal half of the Ad12-specific so-called s...

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Bibliografische gegevens

Gepubliceerd in:	J Virol
Hoofdauteurs:	Pützer, B M, Rumpf, H, Rega, S, Brockmann, D, Esche, H
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	American Society for Microbiology (ASM) 1997
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230261/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9371617/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.12.9538-9548.1997
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