Alternative proteolytic processing of the arterivirus replicase ORF1a polyprotein: evidence that NSP2 acts as a cofactor for the NSP4 serine protease.

The C-terminal half of the replicase ORF1a polyprotein of the arterivirus equine arteritis virus is processed by a chymotrypsinlike serine protease (SP) (E. J. Snijder et al., J. Biol. Chem. 271:4864-4871, 1996) located in nonstructural protein 4 (nsp4). Three probable SP cleavage sites had previous...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Wassenaar, A L, Spaan, W J, Gorbalenya, A E, Snijder, E J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1997
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230234/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9371590/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.12.9313-9322.1997
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