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Shuttling of the herpes simplex virus type 1 regulatory protein ICP27 between the nucleus and cytoplasm mediates the expression of late proteins.

The herpes simplex virus type 1 (HSV-1) immediate-early protein ICP27 is required posttranscriptionally for the expression of HSV-1 late genes during a productive infection. ICP27 also inhibits host cell pre-mRNA splicing, effectively shutting off host cell protein synthesis. Here we describe intrag...

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Detalles Bibliográficos
Publicado en:J Virol
Principais autores: Soliman, T M, Sandri-Goldin, R M, Silverstein, S J
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1997
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230221/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9371577/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.12.9188-9197.1997
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