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Conditionally replicating luciferase reporter phages: improved sensitivity for rapid detection and assessment of drug susceptibility of Mycobacterium tuberculosis.

TM4 is a lytic mycobacteriophage which infects mycobacteria of clinical importance. A luciferase reporter phage, phAE40, has been constructed from TM4 and was previously shown to be useful for the rapid detection and drug susceptibility testing of Mycobacterium tuberculosis. However, the lytic natur...

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Detalhes bibliográficos
Main Authors: Carrière, C, Riska, P F, Zimhony, O, Kriakov, J, Bardarov, S, Burns, J, Chan, J, Jacobs, W R
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC230153/
https://ncbi.nlm.nih.gov/pubmed/9399525
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