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Chromophore structural changes in rhodopsin from nanoseconds to microseconds following pigment photolysis

Rhodopsin is a prototypical G protein-coupled receptor that is activated by photoisomerization of its 11-cis-retinal chromophore. Mutant forms of rhodopsin were prepared in which the carboxylic acid counterion was moved relative to the positively charged chromophore Schiff base. Nanosecond time-reso...

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Autors principals: Jäger, Stefan, Lewis, James W., Zvyaga, Tatyana A., Szundi, Istvan, Sakmar, Thomas P., Kliger, David S.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC23009/
https://ncbi.nlm.nih.gov/pubmed/9238015
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