Chymase cleavage of stem cell factor yields a bioactive, soluble product
Stem cell factor (SCF) is produced by stromal cells as a membrane-bound molecule, which may be proteolytically cleaved at a site close to the membrane to produce a soluble bioactive form. The proteases producing this cleavage are unknown. In this study, we demonstrate that human mast cell chymase, a...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23007/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9256427/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.17.9017 |
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