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Activities and response to DNA damage of latent and active sequence-specific DNA binding forms of mouse p53

The mouse p53 protein generated by alternative splicing (p53as) has amino acid substitutions at its C terminus that result in constitutively active sequence-specific DNA binding (active form), whereas p53 protein itself binds inefficiently (latent form) unless activated by C-terminal modification. E...

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Bibliografiska uppgifter
Huvudupphovsmän: Wu, Yu, Huang, Hua, Miner, Zoe, Kulesz-Martin, Molly
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences of the USA 1997
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC22993/
https://ncbi.nlm.nih.gov/pubmed/9256421
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