Rapid and efficient fusion of phospholipid vesicles by the α-helical core of a SNARE complex in the absence of an N-terminal regulatory domain

A protease-resistant core domain of the neuronal SNARE complex consists of an α-helical bundle similar to the proposed fusogenic core of viral fusion proteins [Skehel, J. J. & Wiley, D. C. (1998) Cell 95, 871–874]. We find that the isolated core of a SNARE complex efficiently fuses artificial bilaye...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Parlati, Francesco, Weber, Thomas, McNew, James A., Westermann, Benedikt, Söllner, Thomas H., Rothman, James E.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22992/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10535962/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.22.12565
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