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Recognition principle of the TAP transporter disclosed by combinatorial peptide libraries

Transport of peptides across the membrane of the endoplasmic reticulum for assembly with MHC class I molecules is an essential step in antigen presentation to cytotoxic T cells. This task is performed by the major histocompatibility complex-encoded transporter associated with antigen processing (TAP...

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Autors principals: Uebel, Stephan, Kraas, Wolfgang, Kienle, Stefan, Wiesmüller, Karl-Heinz, Jung, Günther, Tampé, Robert
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC22991/
https://ncbi.nlm.nih.gov/pubmed/9256420
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