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Identification by mass spectrometry of the phosphorylated residue responsible for activation of the catalytic domain of myosin I heavy chain kinase, a member of the PAK/STE20 family

Myosin I heavy chain kinase from Acanthamoeba castellanii is activated in vitro by autophosphorylation (8–10 mol of P per mol). The catalytically active C-terminal domain produced by trypsin cleavage of the phosphorylated kinase contains 2–3 mol of P per mol. However, the catalytic domain expressed...

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Detalhes bibliográficos
Main Authors: Szczepanowska, Joanna, Zhang, Xiaolong, Herring, Christopher J., Qin, Jun, Korn, Edward D., Brzeska, Hanna
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC22975/
https://ncbi.nlm.nih.gov/pubmed/9238006
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