Genome Reshuffling for Advanced Intercross Permutation (GRAIP): Simulation and Permutation for Advanced Intercross Population Analysis

BACKGROUND: Advanced intercross lines (AIL) are segregating populations created using a multi-generation breeding protocol for fine mapping complex trait loci (QTL) in mice and other organisms. Applying QTL mapping methods for intercross and backcross populations, often followed by naïve permutation...

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Main Authors: Peirce, Jeremy L., Broman, Karl W., Lu, Lu, Chesler, Elissa J., Zhou, Guomin, Airey, David C., Birmingham, Amanda E., Williams, Robert W.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2008
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2295257/
https://ncbi.nlm.nih.gov/pubmed/18431467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001977
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