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Analysis of apoptosis by cytometry using TUNEL assay

Activation of endonucleases that cleave chromosomal DNA preferentially at internucleosomal sections is a hallmark of apoptosis. DNA fragmentation revealed by the presence of a multitude of DNA strand breaks, therefore, is considered to be the gold standard for identification apoptotic cells. Several...

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Bibliografiske detaljer
Main Authors: Darzynkiewicz, Zbigniew, Galkowski, Dariusz, Zhao, Hong
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2295206/
https://ncbi.nlm.nih.gov/pubmed/18314056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2007.11.008
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