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Distinct efficacy of HIV-1 entry inhibitors to prevent cell-to-cell transfer of R5 and X4 viruses across a human placental trophoblast barrier in a reconstitution model in vitro

BACKGROUND AND METHODS: HIV-1 cell-to-cell transmission is more efficient than infection of permissive cells with cell-free particles. The potency of HIV-1 entry inhibitors to inhibit such transmission is not well known. Herein, we evaluated the efficacy of this new class of antiretrovirals to block...

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Detalhes bibliográficos
Main Authors: Ayouba, Ahidjo, Cannou, Claude, Nugeyre, Marie-Thérèse, Barré-Sinoussi, Françoise, Menu, Elisabeth
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2294141/
https://ncbi.nlm.nih.gov/pubmed/18377645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-5-31
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