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Essential and distinct roles of the F-box and helicase domains of Fbh1 in DNA damage repair

BACKGROUND: DNA double-strand breaks (DSBs) are induced by exogenous insults such as ionizing radiation and chemical exposure, and they can also arise as a consequence of stalled or collapsed DNA replication forks. Failure to repair DSBs can lead to genomic instability or cell death and cancer in hi...

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Detalhes bibliográficos
Main Authors: Sakaguchi, Chikako, Morishita, Takashi, Shinagawa, Hideo, Hishida, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2294136/
https://ncbi.nlm.nih.gov/pubmed/18312697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-9-27
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