The AIDS-Like Disease of CD4C/Human Immunodeficiency Virus Transgenic Mice Is Associated with Accumulation of Immature CD11b(Hi) Dendritic Cells

CD4C/human immunodeficiency virus (HIV) transgenic mice develop an AIDS-like disease. We used this model to study the effects of HIV-1 on dendritic cells (DC). We found a progressive decrease in total DC numbers in the lymph nodes, with a significant accumulation of CD11b(Hi) DC. In the thymus, the...

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Bibliografische gegevens

Gepubliceerd in:	J Virol
Hoofdauteurs:	Poudrier, Johanne, Weng, Xiaoduan, Kay, Denis G., Hanna, Zaher, Jolicoeur, Paul
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	American Society for Microbiology (ASM) 2003
Onderwerpen:	Pathogenesis and Immunity
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC229375/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14557658/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.21.11733-11744.2003
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