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Severe CD4(+) T-Cell Depletion in Gut Lymphoid Tissue during Primary Human Immunodeficiency Virus Type 1 Infection and Substantial Delay in Restoration following Highly Active Antiretroviral Therapy

Gut-associated lymphoid tissue (GALT) harbors the majority of T lymphocytes in the body and is an important target for human immunodeficiency virus type 1 (HIV-1). We analyzed longitudinal jejunal biopsy samples from HIV-1-infected patients, during both primary and chronic stages of HIV-1 infection,...

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Detalhes bibliográficos
Main Authors: Guadalupe, Moraima, Reay, Elizabeth, Sankaran, Sumathi, Prindiville, Thomas, Flamm, Jason, McNeil, Andrew, Dandekar, Satya
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC229357/
https://ncbi.nlm.nih.gov/pubmed/14557656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.21.11708-11717.2003
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