A Locus on Mouse Chromosome 6 That Determines Resistance to Herpes Simplex Virus Also Influences Reactivation, While an Unlinked Locus Augments Resistance of Female Mice

During studies to determine a role for tumor necrosis factor (TNF) in herpes simplex virus type 1 (HSV-1) infection using TNF receptor null mutant mice, we discovered a genetic locus, closely linked to the TNF p55 receptor (Tnfrsf1a) gene on mouse chromosome 6 (c6), that determines resistance or sus...

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Bibliographic Details
Main Authors: Lundberg, Patric, Welander, Paula, Openshaw, Harry, Nalbandian, Christina, Edwards, Carl, Moldawer, Lyle, Cantin, Edouard
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC229335/
https://ncbi.nlm.nih.gov/pubmed/14557652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.21.11661-11673.2003
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