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Structural Evidence for Co-evolution of the Regulation of Contraction and Energy Production in Skeletal Muscle
Skeletal muscle phosphorylase kinase (PhK) is a Ca(2+)-dependent enzyme complex, (αβγδ)(4), with the δ subunit being tightly bound endogenous calmodulin. The Ca(2+)-dependent activation of glycogen phosphorylase by PhK couples muscle contraction with glycogen breakdown in the ‘excitation-contraction...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2293304/ https://ncbi.nlm.nih.gov/pubmed/18281058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.12.072 |
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