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Structural Evidence for Co-evolution of the Regulation of Contraction and Energy Production in Skeletal Muscle

Skeletal muscle phosphorylase kinase (PhK) is a Ca(2+)-dependent enzyme complex, (αβγδ)(4), with the δ subunit being tightly bound endogenous calmodulin. The Ca(2+)-dependent activation of glycogen phosphorylase by PhK couples muscle contraction with glycogen breakdown in the ‘excitation-contraction...

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Bibliografiske detaljer
Main Authors: Jeyasingham, Marina D., Artigues, Antonio, Nadeau, Owen W., Carlson, Gerald M.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293304/
https://ncbi.nlm.nih.gov/pubmed/18281058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.12.072
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