Lineage-Specific Amino Acid Substitutions in Region 2 of the RNA Polymerase σ Subunit Affect the Temperature of Promoter Opening

Highly conserved amino acid residues in region 2 of the RNA polymerase σ subunit are known to participate in promoter recognition and opening. We demonstrated that nonconserved residues in this region collectively determine lineage-specific differences in the temperature of promoter opening.

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Bibliographic Details
Main Authors: Barinova, N., Zhilina, E., Bass, I., Nikiforov, V., Kulbachinskiy, A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Genetics and Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293260/
https://ncbi.nlm.nih.gov/pubmed/18281402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00008-08
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