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Ezh2 Requires PHF1 To Efficiently Catalyze H3 Lysine 27 Trimethylation In Vivo

The mammalian Polycomblike protein PHF1 was previously shown to interact with the Polycomb group (PcG) protein Ezh2, a histone methyltransferase whose activity is pivotal in sustaining gene repression during development and in adulthood. As Ezh2 is active only when part of the Polycomb Repressive Co...

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Detalhes bibliográficos
Main Authors: Sarma, Kavitha, Margueron, Raphael, Ivanov, Alexey, Pirrotta, Vincenzo, Reinberg, Danny
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293112/
https://ncbi.nlm.nih.gov/pubmed/18285464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02017-07
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