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Yeast Mpk1 Mitogen-Activated Protein Kinase Activates Transcription through Swi4/Swi6 by a Noncatalytic Mechanism That Requires Upstream Signal

The cell wall integrity mitogen-activated protein kinase (MAPK) cascade of Saccharomyces cerevisiae drives changes in gene expression in response to cell wall stress. We show that the MAPK of this pathway (Mpk1) and its pseudokinase paralog (Mlp1) use a noncatalytic mechanism to activate transcripti...

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Detalhes bibliográficos
Main Authors: Kim, Ki-Young, Truman, Andrew W., Levin, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293104/
https://ncbi.nlm.nih.gov/pubmed/18268013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01795-07
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