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Hydrophobic Inactivation of Influenza Viruses Confers Preservation of Viral Structure with Enhanced Immunogenicity

The use of inactivated influenza virus for the development of vaccines with broad heterosubtypic protection requires selective inactivation techniques that eliminate viral infectivity while preserving structural integrity. Here we tested if a hydrophobic inactivation approach reported for retrovirus...

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Detalhes bibliográficos
Main Authors: Raviv, Yossef, Blumenthal, Robert, Tompkins, S. Mark, Humberd, Jennifer, Hogan, Robert J., Viard, Mathias
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293056/
https://ncbi.nlm.nih.gov/pubmed/18305038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02233-07
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