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Cell Surface Expression of the Vaccinia Virus Complement Control Protein Is Mediated by Interaction with the Viral A56 Protein and Protects Infected Cells from Complement Attack

The vaccinia virus (VACV) complement control protein (VCP) is the major protein secreted from VACV-infected cells. It has been reported that VCP binds to the surfaces of uninfected cells by interacting with heparan sulfate proteoglycans (HSPGs). In this study, we show that VCP is also expressed on t...

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Autors principals: Girgis, Natasha M., DeHaven, Brian C., Fan, Xin, Viner, Kendra M., Shamim, Mohammad, Isaacs, Stuart N.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293032/
https://ncbi.nlm.nih.gov/pubmed/18287241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02426-07
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