Potent Human Immunodeficiency Virus-Neutralizing and Complement Lysis Activities of Antibodies Are Not Obligatorily Linked

To evaluate the contribution of complement-mediated lysis to the in vivo activities of neutralizing antibodies, we analyzed the influence of complement activation on treatment success in a recent passive immunization trial with the neutralizing monoclonal antibodies 2G12, 2F5, and 4E10. Administrati...

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Bibliografische gegevens
Hoofdauteurs: Huber, Michael, von Wyl, Viktor, Ammann, Christoph G., Kuster, Herbert, Stiegler, Gabriela, Katinger, Hermann, Weber, Rainer, Fischer, Marek, Stoiber, Heribert, Günthard, Huldrych F., Trkola, Alexandra
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2008
Onderwerpen:
Pathogenesis and Immunity
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293011/
https://ncbi.nlm.nih.gov/pubmed/18234794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02569-07
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