Differential Inhibition of Nuclear Hormone Receptor-Dependent Hepatitis B Virus Replication by the Small Heterodimer Partner

The nuclear hormone receptors hepatocyte nuclear factor 4 (HNF4) and retinoid X receptor α (RXRα) plus peroxisome proliferator-activated receptor α (PPARα) heterodimer support hepatitis B virus (HBV) pregenomic RNA synthesis and viral replication in nonhepatoma cells. Small heterodimer partner (SHP)...

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Bibliographic Details
Main Authors: Oropeza, Claudia E., Li, Lie, McLachlan, Alan
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292996/
https://ncbi.nlm.nih.gov/pubmed/18234786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02507-07
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