Wheat Germ Cell-Free System-Based Production of Malaria Proteins for Discovery of Novel Vaccine Candidates

One of the major bottlenecks in malaria research has been the difficulty in recombinant protein expression. Here, we report the application of the wheat germ cell-free system for the successful production of malaria proteins. For proof of principle, the Pfs25, PfCSP, and PfAMA1 proteins were chosen....

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Bibliographic Details
Main Authors: Tsuboi, Takafumi, Takeo, Satoru, Iriko, Hideyuki, Jin, Ling, Tsuchimochi, Masateru, Matsuda, Shusaku, Han, Eun-Taek, Otsuki, Hitoshi, Kaneko, Osamu, Sattabongkot, Jetsumon, Udomsangpetch, Rachanee, Sawasaki, Tatsuya, Torii, Motomi, Endo, Yaeta
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Fungal and Parasitic Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292889/
https://ncbi.nlm.nih.gov/pubmed/18268027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01539-07
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