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Bi-Phasic Intensity-Dependent Opioid-Mediated Neural Amplitude Changes in the Chinchilla Cochlea: Partial Blockade by an N-Methyl-d-Aspartate (NMDA)-Receptor Antagonist
Dynorphins, glutamate, and glutamate-sensitive N-Methyl-d-Aspartate (NMDA) receptors exist in the mammalian cochlea. Dynorphins produce neural excitation and excitotoxic effects in the spinal cord through a κ-opioid facilitation of NMDA receptor sensitivity to glutamate. The κ-opioid receptor drug a...
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| Hoofdauteurs: | , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2007
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2292842/ https://ncbi.nlm.nih.gov/pubmed/18036588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2007.10.038 |
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