Worldwide distribution of NAT2 diversity: Implications for NAT2 evolutionary history

BACKGROUND: The N-acetyltransferase 2 (NAT2) gene plays a crucial role in the metabolism of many drugs and xenobiotics. As it represents a likely target of population-specific selection pressures, we fully sequenced the NAT2 coding region in 97 Mandenka individuals from Senegal, and compared these s...

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Autori principali: Sabbagh, Audrey, Langaney, André, Darlu, Pierre, Gérard, Nathalie, Krishnamoorthy, Rajagopal, Poloni, Estella S
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2008
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292740/
https://ncbi.nlm.nih.gov/pubmed/18304320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-9-21
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