Src homology 2 (SH2) domain containing protein tyrosine phosphatase-1 (SHP-1) dephosphorylates VEGF Receptor-2 and attenuates endothelial DNA synthesis, but not migration*

BACKGROUND: Vascular endothelial growth factor receptor-2 (VEGFR-2, KDR), a receptor tyrosine kinase, regulates mitogenic, chemotactic, hyperpermeability, and survival signals in vascular endothelial cells in response to its ligand vascular permeability factor/ vascular endothelial growth factor (VP...

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Bibliographische Detailangaben
Hauptverfasser: Bhattacharya, Resham, Kwon, Junhye, Wang, Enfeng, Mukherjee, Priyabrata, Mukhopadhyay, Debabrata
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2008
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292718/
https://ncbi.nlm.nih.gov/pubmed/18377662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-2187-3-8
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