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MutL homologs in restriction-modification systems and the origin of eukaryotic MORC ATPases

The provenance and biochemical roles of eukaryotic MORC proteins have remained poorly understood since the discovery of their prototype MORC1, which is required for meiotic nuclear division in animals. The MORC family contains a combination of a gyrase, histidine kinase, and MutL (GHKL) and S5 domai...

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Main Authors: Iyer, Lakshminarayan M, Abhiman, Saraswathi, Aravind, L
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292703/
https://ncbi.nlm.nih.gov/pubmed/18346280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-3-8
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