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Experimental evolution and genome sequencing reveal variation in levels of clonal interference in large populations of bacteriophage φX174

BACKGROUND: In large asexual populations where beneficial mutations may co-occur and recombination is absent, the fate of beneficial mutations can be significantly affected by competition (i.e., clonal interference). Theoretical models predict that clonal interference (CI) can slow adaptation, alter...

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Autori principali: Pepin, Kim M, Wichman, Holly A
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292699/
https://ncbi.nlm.nih.gov/pubmed/18366653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-8-85
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