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Testing the Coulomb/Accessible Surface Area solvent model for protein stability, ligand binding, and protein design

BACKGROUND: Protein structure prediction and computational protein design require efficient yet sufficiently accurate descriptions of aqueous solvent. We continue to evaluate the performance of the Coulomb/Accessible Surface Area (CASA) implicit solvent model, in combination with the Charmm19 molecu...

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Autors principals: am Busch, Marcel Schmidt, Lopes, Anne, Amara, Najette, Bathelt, Christine, Simonson, Thomas
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292695/
https://ncbi.nlm.nih.gov/pubmed/18366628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-148
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